Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 5.403


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELK4chr1_-_205600779-0.662.1e-28Click!
ELK1chrX_-_47509864-0.644.9e-27Click!
GABPB1chr15_-_506476040.623.1e-24Click!
GABPAchr21_+_27107257,
chr21_+_27107322		0.486.4e-14Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_137878808 140.853 ETF1
eukaryotic translation termination factor 1
chr2_-_73964427 134.531 NM_016058
 TPRKB
TP53RK binding protein
chr17_+_49230929 128.442 NME1
non-metastatic cells 1, protein (NM23A) expressed in
chr20_-_2451355 126.890 SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr5_-_137878915 126.417 NM_004730
 ETF1
eukaryotic translation termination factor 1
chr20_-_49575038 122.342 NM_003859
 DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr9_+_127631388 114.064 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr21_-_33984865 113.352 NM_021254
 C21orf59
chromosome 21 open reading frame 59
chr17_+_49230896 112.942 NM_000269
NM_198175
NM_001018136
 NME1

NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in

NME1-NME2 readthrough
chr7_-_99698278 112.369 NM_182776
 MCM7
minichromosome maintenance complex component 7
chr1_+_32688053 112.305 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr12_+_69979202 108.652 NM_006431
 CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr1_+_32687970 108.101 NM_003757
 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32688013 107.569 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr12_+_69979268 107.444 CCT2
chaperonin containing TCP1, subunit 2 (beta)
chr20_-_2451428 104.297 SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr1_+_32688010 104.044 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr12_-_110888134 100.469 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr5_-_137878901 96.584 ETF1
eukaryotic translation termination factor 1
chr17_-_17184589 94.441 NM_003653
 COPS3
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 312 entries
enrichment   p-value GO term description
6.24 1.54e-03 GO:0045047 protein targeting to ER
6.24 1.54e-03 GO:0072599 establishment of protein localization in endoplasmic reticulum
4.80 7.08e-03 GO:0042255 ribosome assembly
4.46 2.12e-02 GO:0006376 mRNA splice site selection
4.16 7.25e-03 GO:0006891 intra-Golgi vesicle-mediated transport
4.06 4.11e-03 GO:0048199 vesicle targeting, to, from or within Golgi
4.04 3.04e-02 GO:0070972 protein localization in endoplasmic reticulum
3.97 3.40e-06 GO:0000245 spliceosome assembly
3.86 9.19e-03 GO:0048284 organelle fusion
3.74 2.06e-04 GO:0000387 spliceosomal snRNP assembly
3.74 2.06e-04 GO:0006903 vesicle targeting
3.68 2.69e-14 GO:0000216 M/G1 transition of mitotic cell cycle
3.65 8.57e-09 GO:0006521 regulation of cellular amino acid metabolic process
3.62 2.95e-14 GO:0022618 ribonucleoprotein complex assembly
3.54 1.53e-03 GO:0009452 RNA capping
3.53 3.75e-02 GO:0016236 macroautophagy
3.50 1.97e-02 GO:0006900 membrane budding
3.48 1.17e-13 GO:0071826 ribonucleoprotein complex subunit organization
3.44 1.46e-06 GO:0050434 positive regulation of viral transcription
3.44 5.47e-03 GO:0006370 mRNA capping

Gene overrepresentation in compartment category:

Showing 1 to 20 of 80 entries
enrichment   p-value GO term description
5.11 1.75e-03 GO:0005732 small nucleolar ribonucleoprotein complex
4.85 4.51e-02 GO:0005838 proteasome regulatory particle
4.68 6.00e-03 GO:0022624 proteasome accessory complex
4.32 1.67e-02 GO:0005852 eukaryotic translation initiation factor 3 complex
4.03 1.05e-06 GO:0030532 small nuclear ribonucleoprotein complex
3.99 5.53e-05 GO:0044452 nucleolar part
3.48 4.74e-13 GO:0071013 catalytic step 2 spliceosome
3.47 4.74e-10 GO:0000502 proteasome complex
3.43 4.52e-02 GO:0005839 proteasome core complex
3.26 1.93e-05 GO:0015030 Cajal body
3.17 6.59e-18 GO:0005681 spliceosomal complex
3.12 2.74e-03 GO:0022627 cytosolic small ribosomal subunit
3.04 2.37e-03 GO:0022625 cytosolic large ribosomal subunit
2.95 1.88e-07 GO:0022626 cytosolic ribosome
2.86 2.52e-05 GO:0015934 large ribosomal subunit
2.81 2.70e-50 GO:0030529 ribonucleoprotein complex
2.59 5.45e-03 GO:0015935 small ribosomal subunit
2.57 2.31e-13 GO:0005840 ribosome
2.52 1.90e-05 GO:0042470 melanosome
2.52 1.90e-05 GO:0048770 pigment granule

Gene overrepresentation in function category:

Showing 1 to 20 of 52 entries
enrichment   p-value GO term description
4.16 1.49e-02 GO:0008320 protein transmembrane transporter activity
4.16 1.49e-02 GO:0022884 macromolecule transmembrane transporter activity
2.88 9.46e-03 GO:0032182 small conjugating protein binding
2.87 1.80e-02 GO:0043130 ubiquitin binding
2.86 1.14e-03 GO:0003743 translation initiation factor activity
2.63 3.63e-11 GO:0003735 structural constituent of ribosome
2.54 9.01e-05 GO:0008135 translation factor activity, nucleic acid binding
2.41 3.34e-02 GO:0003697 single-stranded DNA binding
2.38 1.93e-02 GO:0008094 DNA-dependent ATPase activity
2.21 3.85e-04 GO:0051082 unfolded protein binding
2.20 1.12e-02 GO:0008565 protein transporter activity
2.15 1.89e-02 GO:0035257 nuclear hormone receptor binding
2.14 1.31e-34 GO:0003723 RNA binding
2.04 1.99e-02 GO:0008026 ATP-dependent helicase activity
2.04 1.99e-02 GO:0070035 purine NTP-dependent helicase activity
2.02 4.43e-02 GO:0051427 hormone receptor binding
2.00 2.23e-03 GO:0004386 helicase activity
1.94 5.16e-05 GO:0003924 GTPase activity
1.84 4.23e-04 GO:0003713 transcription coactivator activity
1.76 1.80e-03 GO:0019787 small conjugating protein ligase activity